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Lignan derived metabolite associatied with reduced type 2 diabetes mortality

In a recently published study, several researchers from the the Nordic Rye Forum showed for the first time an association between the phytoestrogen enterolactone - a metabolite of plant lignans that are commonly found in rye - and reduced risk of type 2 diabetes mortality.

A number of 450 deceased random cases of diabetes and a randomly selected subcohort of 850 persons, were included in a nested case-cohort from the Danish Diet, Cancer and Health cohort. Pre-diagnostic enterolactone concentrations (measured at baseline, before disease development) were found to be associated with lower mortality, especially deaths from diabetes. The findings call for further exploration of enterolactone in type 2 diabetes management.

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